Quick take: Positive COVID test? Act fast! COVID-19 remains a lethal pandemic. All COVID-19 positive patients should be considered for early treatment, before you get too sick. Highly effective COVID-19 medicines are now widely available. New treatments must be started within the first 5 days, so it is essential to act fast. At least 40% of Massachusetts residents qualify for early at-home treatment. New treatments reduce the risk of serious illness or death by 89%. Detailed information is available at this Massachusetts Department of Public Health website.
Who qualifies to receive early COVID-19 medications?
Adults who have mild-to-moderate COVID-19 and are within five days of symptom onset (7 days for IV medicine), and who are at high risk for serious disease qualify for these highly effective treatments.
Pediatric patients who are at least 12 years old and over 40 pounds qualify for the oral COVID-19 treatments. Infants and children 28 days and older and who weigh at least 7 pounds qualify for intravenous treatment.
Who is at high risk for progression to serious illness or death? Roughly 40% of all Massachusetts residents (more in other states). If you have any of the following conditions, you are at high risk for progression of COVID-19 to serious illness, hospitalization, or death:
Age over 65 years Overweight or obese Diabetic COPD or asthma Diseases of the heart, lung, liver or kidney Pregnant Dementia Cancer Disability Substance use disorder Mental health disorder Immunocompromised The full CDC list is here.
Clinical trials have shown Paxlovid pills reduced the risk of COVID-19 related hospitalization or death by 89% compared to placebo in individuals with mild-to-moderate COVID-19, when given within five days of symptom onset.
Paxlovid pills are currently readily available at many pharmacies including CVS and Walgreens. Urgent care centers and pharmacies with “minute clinic” clinicians can prescribe this medication, often with a telephone or video at-home consultation.
There are currently four COVID-19 treatment options available in Massachusetts today:
2 antiviral pills are available: Paxlovid (must be taken within 5 days of the first COVID-19 symptom) Molnupiravir (must be taken within 5 days of the first COVID-19 symptom)
2 intravenous (IV) treatments are available: Remdesivir, an antiviral medication (must be given within 7 days of the first COVID-19 symptom) Bebtelovimab, a monoclonal antibody treatment that helps your body fight the coronavirus (must be administered within 7 days of the first COVID-19 symptom)
A quick, easy, and free telehealth program for COVID-19 treatment is now also available in Massachusetts:
This program is available to Massachusetts residents 18 years and older who have tested positive for COVID-19, and who are experiencing mild-to-moderate symptoms. If you live in Massachusetts, simply go to this website to obtain a free video telemedicine consultation to determine if you qualify for free treatment. This program is also available in English, Spanish, Haitian Creole, and Portuguese.
For those who do contract COVID-19, whether you are vaccinated or not, if you have even a single risk factor listed above, please talk to your physician or nurse practitioner about taking one of the highly effective medications available, which can dramatically lower your risk of hospitalization and death.
Vaccination: Unvaccinated people are much more likely to be hospitalized and die of COVID-19. Vaccination and staying up to date on COVID-19 boosters continues to be the most effective way to protect yourself against COVID-19.
An infectious disease expert recently told me, “It is not the fault of the unvaccinated that the pandemic continues. However, it is the fault of the unvaccinated when they end up intubated in the hospital ICU.”
How deadly is COVID-19?
COVID-19 was killing 10 times as many people as a bad year of the seasonal flu in 2020 -2021. (COVID-19 has resulted in roughly 500,000 deaths per year in the US in 2020 -2021 rather than 10,000 to 50,000 deaths per year typically seen in the US due to the flu). Today, the Omicron variant of COVID-19 is killing five times as many people as a bad year for the seasonal flu (roughly 500 COVID-19 deaths per day in the US rather than 100 flu deaths per day due to a bad seasonal flu).
You may be through with COVID, but COVID may not be through with you.
The omicron variant of COVID-19 is not milder than the earlier versions of COVID-19. A new Harvard study concludes that fewer people are dying of COVID today due to prior vaccination or partial immunity from prior infection, not because omicron itself is mild. Omicron is deadly. Please contact your healthcare provider urgently if you test positive for COVID-19. Lifesaving treatments are available.
Monoclonal antibody therapy is an important but underused treatment for preventing severe disease and death from COVID-19.
Monoclonal antibody therapy is the best available therapy for people over 12 years of age who test positive for COVID-19 and who have risk factors for severe disease.
It reduces hospitalizations and death by 75% to 85%.
It is provided free of charge to any US resident.
Real fast take: Monoclonal antibody therapy is safe; it’s effective and it saves lives: use it!
Monoclonal Antibody Therapy:
Monoclonal antibody therapy is the most effective treatment to date to prevent patients with mild or moderate cases of COVID-19 from developing severe disease, hospitalization, ICU admission, intubation and death. Monoclonal antibody therapy reduces the number of viruses in the patient and lessens symptom severity. It has been demonstrated to reduce COVID-19 hospitalizations and death by 75% to 85%.
When administered within 10 days of onset of COVID-19 symptoms, this one-time treatment is highly effective in killing the virus, preventing symptoms from worsening, and avoiding hospitalization. When administered early, many patients report a rapid and complete resolution of symptoms.
Please remember, monoclonal antibody therapy is not a substitution for vaccination. Vaccination is still the best first line of defense against COVID-19.
What is monoclonal antibody therapy?
This medication consists of antibodies to the virus, quite similar to the antibodies that your own body makes when you are vaccinated or infected with the virus. However, the therapy gives patients an immediate boost in the number of these antibodies. These antibodies are synthesized in a lab. They do not come from other patients.
The monoclonal antibodies kill the virus early before the virus can multiply and make a patient very sick. These antibodies attack the so-called spike protein on the virus, blocking the virus from attaching to a patient’s cells. This slows the growth of the virus within the patient, while the patient’s own body revs up its own natural immunity systems.
The US Food and Drug Administration (FDA) issued emergency use authorization for monoclonal treatments for COVID-19 patients or exposed people, aged 12 and older, who are at moderate or high risk for developing severe COVID-19 disease. This includes many or most adult COVID-19 patients in the US.
Monoclonal antibody therapy involves administering a small amount of medication intravenously (into your vein) over 20 to 30 minutes, or it can be administered subcutaneously (as injections under your skin). The single treatment is followed by an hour of patient monitoring.
This therapy can be administered in an outpatient medical clinic, an emergency room, a long-term care setting such as a nursing home or even in a patient’s home.
For those who would like a more in-depth discussion of the benefits of monoclonal antibody therapy, here is the link to a one hour webinar, with 5 Massachusetts experts, which I moderated for the Massachusetts Health & Hospital Association’s physician leaders on November 22, 2021.
Which patients are eligible to receive monoclonal antibody therapy?
This medication is available for use in patients who are not yet sick enough to be hospitalized and who are at an increased risk for progression to severe disease, hospitalization, and death and who are at least 12 years old.
This therapy can also be given to high-risk patients (for example, nursing home residents) who have simply been exposed to COVID-19, prior to testing positive for COVID-19. We call this prophylactic therapy.
Who is considered at increased risk for severe COVID-19 disease, and therefore an ideal candidate for early treatment with this life-saving disease as an outpatient?
If you have tested positive for COVID-19 within the past 10 days, please contact your healthcare professional to discuss monoclonal antibody therapy. The sooner, the better.
Are there side effects to monoclonal antibody treatment?
Allergic reactions can happen with the administration of this medication, like any medication. Patients are therefore evaluated for the development of any signs of allergic reaction for one hour after this one-time treatment.
Most experts believe that these antibodies may limit your own body’s ability to develop an immune response during a subsequent COVID-19 vaccination for a brief period of time. Hence currently, it is recommended that patients delay COVID-19 vaccination for 90 days after receiving monoclonal antibody treatment. Other rare side effects can occur. Feel free to discuss this with your healthcare provider.
Do yourself a favor; do your family and friends a favor and do me a favor; if you test positive for COVID-19 and qualify for this life saving treatment, seek it out. The life you save may be your own.
While the causes of physician burnout (and clinician burnout more generally) are multifactorial, inefficient electronic medical records (EHRs) and their associated disrupted workflows consistently top the list of the main drivers of physician burnout. Atul Gawande wrote an eloquent piece on the subject entitled, Why doctors Hate Their Computers, in which Dr. Gawande notes “I’ve come to feel that a system that promised to increase my mastery over my work has, instead, increased my work’s mastery over me.”
There are EHR optimization pearls your organization can take.
But there are practical EHR optimization pearls any organization can take to reduce administrivia driven burnout. Last week, I co-authored a paper for the Joint Massachusetts Medical Society (MMS) – Massachusetts Health & Hospital Association (MHA) Task Force on Physician Burnout in partnership with the Reliant Medical Group: Changing the EHR from a Liability to an Asset to Reduce Physician Burnout.
This paper includes more than a dozen electronic health record (EHR) optimization techniques organizations can take today to improve the usability of the EHR as well as its associated workflows, in order to reduce unnecessary administrative burden for physicians and other clinicians.
Our message is that there are many interventions compassionate leaders can take today to help mitigate the drivers of clinician burnout. We would be happy to hear what has worked for you.
Each year, the graduating classes of three average size medical schools don’t add a single physician to the US workforce; they simply replace the 300 to 400 physicians the American Foundation for Suicide Prevention estimates kill themselves each year. We lose a doctor a day to suicide.
In a recent blog
post a healthcare CEO asked, “Is the rate of physician suicide
statistically different from that of other highly paid
professionals?” Yes.
The American
Psychiatric Association reported that physicians have the highest
suicide rate of any profession at their annual
meeting in 2018, higher in fact than active duty military personnel.
The time to prevent
physician suicide, rigorously document its occurrence, remove the
stigma of seeking mental health care and to care for suicide victims’
workplace survivors is long overdue.
Physicians know how
to stay healthy. This is why it is especially tragic that the only
cause of death where the risk to physicians is higher than the
general public is suicide.
Worse, we’ve
been aware of this slow motion tragedy for generations and it is
largely preventable. S. Dana Hubbard, M. D., Director, Bureau of
Public Health Education, New York City Department of Health published
the fact that physicians lead the list of suicides by professions in
the American Journal of Public Health, in 1922.
Almost a century
later mystery still shrouds the exact number of physician suicides
each year as families and employers alike are reluctant to tell the
truth in public, due to the fear of stigma. Medical examiners may
have difficulty distinguishing intentional from unintentional
traumatic deaths. Even when a suicide is accurately determined, there
is no consistent reporting of the victim’s occupation.
Most experts agree the physician suicide rate is roughly twice that of the US population in general, and it is even worse for female physicians. A meta-analysis of physician suicide published in the American Journal of psychiatry demonstrated that both male and females physicians are more likely to die by suicide compared to the general population (1.41 times more likely for male physicians and 2.27 times more likely for female physicians).
The
US healthcare system is killing physicians.
Students and young Physicians have been documented to be actually more resilient and less depressed than the US average. Then we are subjected to stress, moral distress and trained to ignore the symptoms of depression until it is too late. A study published in the Archives of General Psychiatry demonstrated that the rate of depression among physicians immediately prior to entering internship was 3.9%. During internship, this rate skyrocketed to 25.7%.
Factors contributing
to the epidemic of physician suicide include:
Repetitive
exposure to death and dying
Exact knowledge
of (and ready access to) lethal means
Stigma
associated with asking for mental healthcare and
Our
profession’s excessive dependence on self-reliance.
While the first two
factors above are likely inherent to the profession, the latter
two factors driving suicide are amenable to mitigation.
Here are Ten Suggestions for 2019:
Put an end to the silent curriculum (“Don’t ask for help. Never show weakness.”) in physician training programs.
Part of the reason
physicians don’t ask for help is that in training we were taught
the unwritten rule: “Don’t ask for help and never show
weakness.”
On my first day of surgical internship, I was naturally a bit apprehensive, given the enormous privilege and responsibility I was about to be given, caring for, and operating on some of the most ill patients in one of the finest academic medical centers in the US. I was shocked and taken aback by the advice the entire group of us surgical interns were given by the senior attending surgeon, tasked with orienting us. He said, “Always remember that while you are here… you are swimming with sharks. So don’t make waves, and if you are bit, don’t bleed.” It is this kind of abusive attitude which I am confident cost one of my female classmates her life, during her surgical residency when she killed herself halfway across the country in another surgical training program.
We must incorporate wellness into both the written (and silent) curriculum.
2. The Physicians need better access to mental health care without fear of punishment for admitting they need help.
Dr. Michell
Hardison, a well-respected family doctor in Raleigh NC chose suicide
over psychiatric care for his depression. His daughter
Anna Hardison Severn revealed, “He was 100% positive that if he
came forward and said he needed help that there would be a reprisal
of some kind.”
State medical boards
are responsible for licensing physicians and protecting the public by
ensuring physicians meet high standards. There is nothing wrong with
medical boards asking physicians if they have a medical or
psychiatric condition which might lower the quality of the care they
deliver. They should not however ask if a physician has ever been
under the care of a mental health professional. For if they do
this, physicians will forgo needed care which could harm the doctor
and jeopardize the quality of the care for their patients.
The Federation of State Medical Boards (FSMB) Workgroup on Physician Wellness and Burnout made 35 recommendations to better address physician burnout. These recommendations should be adopted by all states. They advise against asking probing personal questions regarding a physician’s mental health. The FSMB specifically recommended that state medical boards indicate“it is not only normal but anticipated and acceptable for a physician to feel overwhelmed from time to time and to seek help when appropriate.”
3. Not only should the electronic medical record must be optimized, but processes and systems must be optimized in order to get the most out of this technology and improve user satisfaction.
How it is that
healthcare is the only industry where digitization/computerization
has decreased worker productivity? The epidemic of physician
burnout, driven by administrative hassles, loss of professional
autonomy and increasing workloads is contributing to physician
burnout, depression and suicide.
It is inexcusable
that for every hour physicians spend facing a patient in their
office, they
are forced to spend two hours tending to desk work and
documentation in the electronic medical record.
At UC Davis Medical Health, Scott MacDonald, MD, FACEP demonstrated that by optimizing their electronic medical record’s use, the health system could both dramatically increase physician satisfaction with their EHR and improve their quality of life. They were able to eliminate over 25 hours of unproductive, unnecessary busy work from their physicians’ schedule each month! Imagine how much more time physicians could spend meaningfully caring for their patients and achieving work life balance if this innovation were to be adopted nationwide.
4. Stop the stigma. Employers of physicians, including hospitals, physician groups and residencies must encourage and normalize accessing mental health care.
We must destigmatize and treat physician depression in order to prevent suicide. One study found that access to residency positions was limited for fully qualified students who had requested psychiatric counseling! Only when seeking out a councilor is considered “normal” will physicians ask for help when they need it. All too often, physicians are encouraged to keep vulnerabilities hidden and not ask for help.
5. The practice of requiring medical students and residents to obtain mental health care at their own institution limits confidentiality and should be eliminated.
Until the stigma of obtaining mental health is completely relegated to the ash-bin of history, the confidentiality of accessing such services is critical, particularly for physicians in training. Some student and resident health plans require trainees to obtain healthcare at their own institution, limiting confidentiality for both physical and psychiatric conditions. This paternalistic and antiquated requirement should be eliminated.
6. Peer support should be available at times of great vulnerability:
Medical errors,
patient injuries and patient deaths are obviously painful for the
patient’s families. Less well understood is the fact that
physicians also suffer emotionally in such circumstances,
particularly if they believe they have somehow failed their patient
and begin to second-guess their own competence.
In times of great stress, such as these or when facing a medical malpractice lawsuit, physicians are extra vulnerable to depression and suicide. It is at these times that confidential peer support, advice from a colleague who has endured the same stressor is most helpful. Employers should plan ahead for such events and offer well-structured and readily available confidential peer to peer support programs to their employed and affiliated physicians.
7. We must accurately keep track of suicide rates by profession. State medical examiners should record the occupation of all suicide victims, including what school they are attending if they are in college or graduate school.
Only then can we
identify opportunities for improvement and evaluate whether our
interventions are effective in stemming the tide of this horrific
slow motion tragedy.
This would capture both the number of physicians / medical students who are committing suicide, and also spotlight any outlier institutions.
8. Postvention: Care for the bystanders after a physician suicide is essential.
Post-suicide counseling and peer support is especially important after a colleague has committed suicide. Toolkits such as the American Foundation for Suicide Prevention’s toolkits are available on line. There is even a toolkit specifically designed for medical schools to utilize after a medical student suicide.
9. Encourage all physicians to select their own trusted primary care physician (and regularly check in with that physician).
All too often physicians follow the dictum, “physician heal thyself.” Employers and affiliated institutions should encourage all medical students, residents and practicing physicians to choose their own trusted primary care physician. In addition to obtaining objective evidence based care from a personal physician, these trusted doctors represent another touch point from which distressed physicians can obtain emotional support.
10. Accessing medical care, whether physical or psychiatric, should be modeled by mentor physicians.
Organizational
leaders should model self-care, access mental health care publicly
and publicly reinforce the necessity of a healthy work-life balance.
Together we can
end the epidemic of physician suicide. Let’s make it happen in
2019.